ABSTRACTS OF PAPERS AT THE 63TH RESEARCH MEETING OF THE MEDICAL RESEARCH CENTRE OF BOMBAY HOSPITAL ON MONDAY, 8TH FEBRUARY 1999, 2.30 PM IN THE SP JAIN CAFETERIA (CONVENOR DR. HL DHAR)
1. COLOUR DOPPLER ULTRASOUND IN RENAL TRANSPLANTS
JT Jagose, AK Dalal, Sandeep Punamiya, AL Kirpalani
Doppler ultrasound is a useful, non-invasive modality to monitor allograft dysfunction.
38 live donor transplants were evaluated by performing 90 colour doppler and B-mode ultrasound studies during the post operative period. Of the 90 studies, 50 were performed in 18 patients with normally functioning allografts and 40 studies in 20 patients with renal dysfunction.
It was found that the RI (Resistive Index) as defined by Pourcelot of the arcuate arteries were 0.56 æ 0.073 in those with normal renal function and ranging from 0.70 æ 0.114 to 0.88 æ 0.084 in cases of rejection including other causes of graft dysfunction.
The wave form pattern analysis as classified into 6 types revealed that types 2,4 and 6 were seen during rejection and renal dysfunction of other aetiologies, type 1 was not diagnostic of normalcy, whereas type 3 excluded abnormality.
B-mode grey scale findings, especially, prominence of pyramids and increased cortical echogenicity were found to have a supportive value in the differential diagnosis of graft dysfunction.
We conclude that though renal biopsy remains the gold standard for diagnosis of renal dysfunction; colour doppler ultrasound is a useful, non-invasive, although costly imaging modality in the evaluation of renal allografts. We feel that its routine use in normally functioning allografts is therefore not justifiable.
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